Neuropediatrics 2019; 50(04): 253-256
DOI: 10.1055/s-0039-1692417
Short Communication
Georg Thieme Verlag KG Stuttgart · New York

N-Methyl-D-Aspartate Receptor Encephalitis with Psychiatric Symptoms and an Ovarian Teratoma Detected by MRI in a 17-Year-Old Girl

A. Barth
1   Department of Pediatric Neurology, Children's Hospital Datteln, University Witten/Herdecke, Germany
,
I. Nassenstein
2   Department of Radiology, Children's Hospital Datteln, University Witten/Herdecke, Germany
,
R.B. Tröbs
3   Department of Pediatric Surgery, Marien Hospital Herne, Ruhr-University Bochum, Germany
,
A. Tannapfel
4   Institute of Pathology, Ruhr-University Bochum, Bochum, Germany
,
H. Dercks
5   Department of Pediatric Child Psychiatry, Children's Hospital Datteln, University Witten/Herdecke, Germany
,
K. Rostásy
1   Department of Pediatric Neurology, Children's Hospital Datteln, University Witten/Herdecke, Germany
,
A. Wegener-Panzer
2   Department of Radiology, Children's Hospital Datteln, University Witten/Herdecke, Germany
› Author Affiliations

Funding This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.
Further Information

Publication History

05 March 2019

27 April 2019

Publication Date:
04 June 2019 (online)

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Abstract

N-methyl-D-aspartate receptor (NMDAR) encephalitis is a rare antibody-mediated autoimmune encephalitis often associated with an ovarian teratoma in adolescent females. Here we present a 17-year-old girl with only and unusual psychiatric symptoms as part of her NMDAR encephalitis in combination with a very small ovarian teratoma suspected by magnetic resonance (MR) imaging and finally histologically confirmed. We further review the literature of NMDAR encephalitis in combination with an ovarian teratoma and discuss the recommended radiological workup in children with a suspected ovarian tumor.